Dr. William Liou's Research


Dr. William Liou

The computational engineering physics research in Dr. William W. Liou’s group includes the following topics in the last two years.

(1) Computational modeling of reverse shoulder arthroplasty. In collaboration with Wayne State University Medical School and with funding support from ExacTech Inc., Dr. Liou’s group conducted physics-based computations of the muscle strength and joint forces associated with reserve shoulder arthroplasty (RSA). RSA’s indications include many complex etiologies and the operation has become increasingly common in shoulder implants. Dr. Liou used human musculoskeletal models to simulate the effects of RSA shoulder implant on muscle forces and joint reaction forces during motions of arms. The shoulder muscle groups and bones are modeled using a finite element method.

(2) Computational simulation of heart health using hemodynamics models. It is widely known that chronic high sodium intake contributes to the development of hypertension and left ventricular hypertrophy. A system-level computer model that included cardiovascular hemodynamics and kidney function were developed to simulate the long-term effects of increased sodium intake on the left ventricular mechanical functions and the body-fluid homeostasis. The results may be used to provide information on how much salt is too much for an individual. Dr. Liou’s group also studied the cardiovascular health by simulating the short- and long-term responses of, for example, blood pressure, heart rate, hormonal concentrations, and cardiac structural changes to fluid overload. The efforts were partially supported by Borgess Medical Center and Western Michigan University Office of Vice President for Research.

(3) Fluid flow and flexible structure interactions. The interaction between fluid medium and the solid affects the performance of components of ground vehicle systems, such as fan drives, hydraulic fluid lines, fluid mixing chambers, and cooling fan.   Computational fluid dynamics (CFD) and finite element computational structure dynamics (CSD) methods are coupled. Supported by the CAViDS Consortium at the College of Engineering and Applied Sciences at WMU, multiple commercial CFD and CSD software were applied to identify approaches that are likely to be developed to form best practices in production vehicle applications.  Research was also performed in the areas of flexible wing drag reduction, wing surface roughness simulations, and conjugate heat transfer in engine exhaust and arterial atherosclerotic plagues. 


Research results and publications can be found at the homepage of Dr. William W. Liou.

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