Flexible and Wireless Estrogen Sensing Device

A lightweight, portable sensing system was developed as a means to detect the amount of estradiol (E2) in a solution of 0.1 M phosphate buffer. This was done by screen printing a 3-electrode sensor made from a silver/silver chloride counter electrode, silver reference electrode, and carbon/ordered mesoporous carbon/graphite working electrode. This sensor was connected to a data acquisition circuit designed for this project in particular, consisting of the LMP91000, a low-power analog front end (AFE) potentiostat paired with the ESP32 microprocessor. This circuit was equipped with a USB connection for the purpose of data acquisition and programming, as well as a OLED digital display and a Bluetooth antenna to display data via Bluetooth connectivity. This apparatus was found to detect estrogen successfully in the range of 5 nM through 5 uM with the following relationship:

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